Tag: Audience: Healthcare Professionals

Clinical Trial Abstracts

Non-pharmaceutical treatments for irritable bowel syndrome

Authors: Wang XJ, Thakur E, Shapiro J Journal: BMJ Year: 2024 Volume: 387 Article number: e075777 DOI: 10.1136/bmj-2023-075777 Study at a glance Study type: State of the art review Studies included: Multiple randomised controlled trials, systematic reviews, and meta-analyses Participants: Adults with irritable bowel syndrome Intervention: Non-pharmaceutical treatments including dietary interventions, brain-gut behaviour therapies, complementary […]

Clinical Trial Abstracts

Lifestyle, behaviour, and environmental modification for the management of patients with IBD

Authors: Ashwin N Ananthakrishnan, Gilaad G Kaplan, Charles N Bernstein, Kristin E Burke, Paul J Lochhead, Alexa N Sasson, Manasi Agrawal, Jimmy Ho Tuan Tiong, Joshua Steinberg, Wolfgang Kruis, Flavio Steinwurz, Vineet Ahuja, Siew C Ng, David T Rubin, Jean-Frederic Colombel, Richard Gearry, on behalf of the International Organization for Study of Inflammatory Bowel Diseases […]

Clinical Trial Abstracts

AGA Clinical Practice Update on Diet and Nutritional Therapies in Patients With Inflammatory Bowel Disease: Expert Review

Authors: Jana G. Hashash, Jaclyn Elkins, James D. Lewis, and David G. Binion Journal: Gastroenterology Year: 2024 Volume: 166 Pages: 521–532 DOI: 10.1053/j.gastro.2023.11.303 Study at a Glance Study type: Expert review Participants: Not applicable (expert guidance document) Population studied: Patients with inflammatory bowel disease (IBD) Intervention or approach studied: Diet and nutritional therapies, including Mediterranean […]

Healthcare News

Three Studies Highlight Shift Towards Precision Medicine in IBD

Three recently reported developments in inflammatory bowel disease (IBD) research underscore a growing shift towards mechanism-based, personalised treatment. The findings address long-standing questions about why Crohn’s disease and ulcerative colitis affect individuals differently and why many patients continue to experience disease instability despite advanced therapies. Background Context IBD encompasses a spectrum of chronic inflammatory conditions […]

Healthcare News

Hidden Cell Network May Hold Key to Intestinal Repair in IBD

Researchers have identified a previously unrecognised network of cells in the intestine that could offer new insights into tissue healing and inflammatory bowel disease. The discovery, announced by EurekAlert!, may help explain why some patients experience impaired gut repair and could inform future therapeutic strategies for Crohn’s disease and ulcerative colitis. Background Context The intestinal […]

Clinical Trial Abstracts

Modern Advanced Therapies for Inflammatory Bowel Diseases: Practical Considerations and Positioning

Authors: David I. Fudman, Ryan A. McConnell, Christina Ha, and Siddharth Singh Journal: Clinical Gastroenterology and Hepatology Year: 2025 Volume: 23 Pages: 454–468 DOI: https://doi.org/10.1016/j.cgh.2024.06.050 Study at a Glance Study type: Narrative review Participants: Not applicable Population studied: Patients with inflammatory bowel disease Intervention or approach studied: Janus kinase inhibitors, interleukin-23 antagonists, and sphingosine 1-phosphate […]

Clinical Trial Abstracts

Diet in Inflammatory Bowel Diseases: Efficacy, Tolerability, and Microbiome Effects Toward Personalized Management

Francesco Calabrese and colleagues from the University of Genoa have published a comprehensive review examining the role of diet as a potential therapeutic tool in inflammatory bowel disease. Their work, published in Digestive Diseases and Sciences in 2025, explores how various dietary approaches may influence symptoms, intestinal inflammation, the gut microbiome, and mucosal repair in […]

Clinical Trial Abstracts

Dietary Behaviors and Beliefs in Patients with Inflammatory Bowel Disease

Authors: Małgorzata Godala, Ewelina Gaszyńska, Łukasz Durko, Ewa Małecka-Wojciesko Journal: Journal of Clinical Medicine Year: 2023 Volume: 12 Article number: 3455 DOI: 10.3390/jcm12103455 Study at a Glance Study type: Prospective questionnaire study Participants: 82 adults with inflammatory bowel disease (IBD) Population studied: 48 people with Crohn’s disease and 34 with ulcerative colitis Intervention or approach […]

Clinical Trial Abstracts

Irritable Bowel Syndrome in Inflammatory Bowel Disease: An Evidence-Based Practical Review

Authors: Mohsin F. Butt, Mustafa H. Reghefaoui, Aaron Shailesh Benedict, Maiss Reghefaoui, Hussain Al-Jabir, Aneeqa Shaikh, Katarina Vojtekova, Gordon W. Moran, Maura Corsetti and Qasim Aziz Journal: Journal of Clinical Medicine Year: 2025 Volume: 15 Page number: 116 DOI: 10.3390/jcm15010116 Study at a Glance Study type: Narrative review Participants: Patients with quiescent inflammatory bowel disease […]

Healthcare News

Oxford researchers identify anti-IL-10 autoantibodies in subset of IBD patients

Researchers from the University of Oxford, Newcastle University, and the University of Cambridge have identified autoantibodies against interleukin-10 (IL-10) in approximately 3.5% of inflammatory bowel disease (IBD) patients, offering a biological explanation for a genetic marker previously linked to severe disease and pointing toward more targeted treatment strategies. Background Context Interleukin-10 is a key regulatory […]

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