Duvakitug, an investigational monoclonal antibody targeting interleukin-23, has demonstrated efficacy as an induction therapy for patients with inflammatory bowel disease (IBD), according to new research reported in MedPage Today. The findings add to the evolving landscape of advanced biologics for Crohn’s disease and ulcerative colitis. Background Context Interleukin-23 (IL-23) is a pro-inflammatory cytokine that plays […]
Lifestyle factors, genetic susceptibility, and risk of incident diverticulitis: an integrated analysis of four prospective cohort studies and electronic health records-linked biobank
Authors: Wenjie Ma, Jane Ha, Christopher J. Neylan, Heather Munro, Duncan Skerrett, Jonathan M. Downie, Magdalena Sevilla-González, Mark Steinwandel, Michael Mumma, Wei Zheng, Lillias H. Maguire, Edward L. Giovannucci, Lisa L. Strate, Andrew T. Chan Journal: Gut Year: 2025 Volume: 74 Pages: 2004–2011 DOI: 10.1136/gutjnl-2025-335364 Study at a glance Study type: Integrated analysis of prospective […]
The Mediterranean Diet and Inflammatory Bowel Disease: A Comprehensive Systematic Review and Meta-Analysis
Authors: Muhammad Shahzil, Syeda Kanza Kazmi, Minahel Shehzadi, Fariha Hasan, Mohammad Waqas Danish, Muhammad Saad Faisal, Justin Canakis, Kofi Clarke Journal: Gastroenterology Research and Practice Year: 2026 Volume: 2026 **Article…
Gut microbiome composition and metabolic activity in women with diverticulitis
Article information Authors: Ma W, Wang Y, Nguyen LH, Mehta RS, Ha J, Bhosle A, Mclver LJ, Song M, Clish CB, Strate LL, Huttenhower C, Chan AT Journal: Nature Communications Year: 2024 Volume: 15 Page number(s): 3612 DOI: 10.1038/s41467-024-47859-4 Study at a glance Study type: Nested case-control study Number of studies: Not applicable Participants: 242 […]
Gut micro-organisms associated with health, nutrition and dietary interventions
Authors: Francesco Asnicar, Paolo Manghi, Gloria Fackelmann, Gabriel Baldanzi, Elco Bakker, Liviana Ricci, Gianmarco Piccinno, Elisa Piperni, Katarina Mladenovic, Federica Amati, Alberto Arrè, Sajaysurya Ganesh, Francesca Giordano, Richard Davies, Jonathan…
Epidemiology, pathogenesis, diagnosis, and treatment of inflammatory bowel disease: Insights from the past two years
Article information Authors: Jian Wan, Jiaming Zhou, Zhuo Wang, Dan Liu, Hao Zhang, Shengmao Xie, Kaichun Wu Journal: Chinese Medical Journal Year: 2025 Volume: 138 Issue: 7 Pages: 763-776…
New Ultrasound Platform Trialled for Imaging Rectal Lesions in Outpatient Clinic
Doctors in the United States have reported the first use of a new ultrasound imaging system to examine growths in the rectum during outpatient procedures. The technology, which combines imaging with treatment capabilities, was used successfully in two patients at an ambulatory surgical centre. What the team reported The medical team from HCA Healthcare published […]
Interplay of probiotics, prebiotics, synbiotics and postbiotics: a review of their therapeutic potential for gastrointestinal inflammation
Authors: Radhika Baheti, Sanjeevani Deshkar, Shivani Jadhav, Kanchan Mule, Abhishek Jha, Prabhanjan Giram, Jayashri Mahore Journal: Food Research International Year: 2026 Volume: 230 Article number: 118598 DOI: 10.1016/j.foodres.2026.118598 — ##…
Nutritional composition of diets for inducing and maintaining remission in inflammatory bowel diseases: from bedside to plate
Article information Authors: L. Godny, T. Pfeffer-Gik, S. Elial-Fatal, S. Shakhman, I. Dotan Journal: Current Opinion in Pharmacology Year: 2026 Volume: 86 Article number: 102587 DOI: https://doi.org/10.1016/j.coph.2025.102587 Study…
JAK inhibitor shows promise for perianal Crohn’s disease in real-world study
A medicine already used to treat inflammatory bowel disease (IBD) may help people with a difficult form of Crohn’s disease affecting the area around the anus, according to research published…