Clinical Reviews

inflammatory bowel Mozaffari H, Daneshzad E, Larijani B, Bellissimo N, Azadbakht L. European Journal of Nutrition. 2020;59(1):1–17. DOI: 10.1007/s00394-019-01901-0 Background & Rationale Inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), has shown increasing incidence globally, with the highest rates reported in Europe and North America. While genetic factors contribute approximately 25% […]

Protected from Colitis through Anti-Inflammatory Mechanisms Background & Rationale The role of omega-6 (n-6) and omega-3 (n-3) polyunsaturated fatty acids (PUFA) in the regulation of inflammation has been a topic of interest in the field of gastroenterology. While n-6 PUFA are known to promote inflammation, n-3 PUFA have been shown to have anti-inflammatory properties. The […]

Beneficial Effects of Omega-3 Fatty Acids in Chronic Inflammatory Diseases Background & Rationale The omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been shown to possess anti-inflammatory properties, suggesting a potential therapeutic role in chronic inflammatory diseases. This review aims to discuss the pharmacology and therapeutics of n-3 […]