Eli Lilly has announced it will present new research findings on several of its skin condition treatments at a dermatology conference this October, including studies on a psoriasis medicine called…
For many people with ulcerative colitis, diet feels like a daily puzzle: some foods settle things, others stir them up, and it is not always clear why. Part of the answer may lie not in the food itself, but in what happens to it after it reaches the colon, where trillions of bacteria break it […]
Many people with inflammatory bowel disease (IBD) are told to “feed their gut bacteria” or eat more fibre, without ever being told why. One of the clearest answers lies in a single molecule produced during digestion: butyrate. Understanding what it does helps explain why diet, the gut lining, and inflammation are so closely linked. What […]
Many people with inflammatory bowel disease (IBD) think carefully about diet, not just for comfort but because what they eat seems to influence how settled or reactive the gut feels. Two substances that come up repeatedly in gut health research, eicosapentaenoic acid (EPA), an omega-3 fatty acid, and butyrate, a short-chain fatty acid (SCFA), work […]
An experimental medicine for a difficult-to-treat form of Crohn’s disease has shown promising results in an extended study, according to its developer, Agomab Therapeutics. The company reported that most participants taking the drug, called ontunisertib, remained in remission after nearly a year of treatment. The findings could be relevant for people living with Crohn’s disease […]
Children with Crohn’s disease who switch from one biologic medicine to another may need different blood level targets than those starting treatment for the first time, according to a new study. Researchers found that children who moved from adalimumab to infliximab had lower infliximab levels in their blood, yet still reached similar remission rates. The […]
Many people with Crohn’s disease or ulcerative colitis only think to ask about psychological support after months, or years, of quietly struggling with anxiety, low mood, or the exhausting unpredictability of flares. Yet the gut and brain are in constant two-way communication, and addressing the psychological side of a gut condition is not an admission […]
For many people with chronic, watery diarrhoea, a colonoscopy comes back “normal”, and that can feel more frustrating than reassuring. The bowel lining looks healthy to the naked eye, yet the symptoms persist, sometimes for months before an answer is found. This is often the experience of people with microscopic colitis, a form of bowel […]
Many people with inflammatory bowel disease (IBD) notice that diet seems to influence how they feel, even when no single “trigger food” can be identified. Part of the explanation may lie not in what irritates the gut, but in what nourishes it. One of the most studied compounds here is butyrate, a substance made by […]
A new engineering review has outlined nanomaterial based drug delivery platforms designed to exploit differences in enzyme activity between the healthy gut microbiome and inflamed colonic tissue in inflammatory bowel disease (IBD). Published in the International Journal of Nanomedicine, the work describes how these engineered carriers could allow treatments to be released more precisely at […]
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