Johnson & Johnson has reported two-year results for icotrokinra, an oral medicine for moderate to severe plaque psoriasis, a long-term skin condition that causes raised, scaly patches. The findings, presented at a dermatology conference, showed that many people kept clear or almost clear skin over two years of treatment. Because the medicine blocks a target […]
Butyrate and IBS: Could Short-Chain Fatty Acids Influence Your Symptoms?
Many people living with irritable bowel syndrome (IBS) describe a frustrating pattern: bloating that comes and goes, stool that swings between loose and hard, and a sense that their gut is simply unpredictable. For some, this happens alongside inflammatory bowel disease (IBD), particularly once inflammation has settled but symptoms persist. One area of growing scientific […]
Butyrate and Crohn’s Disease: What the Research Shows Beyond Ulcerative Colitis
Many people with Crohn’s disease have heard that butyrate, a substance made by gut bacteria, is good for the bowel. Most of this discussion, however, comes from research in ulcerative colitis (UC), which affects only the large bowel. Crohn’s disease is different: it can involve any part of the digestive tract, and this distinction matters […]
Vitamin D Levels May Reflect Disease Activity in IBD
A new study has found that people with inflammatory bowel disease (IBD) tend to have lower vitamin D levels than those without the condition, and that levels drop further during flare-ups. Vance Health Hub reports on findings suggesting that blood vitamin D tests could, in future, help doctors track how active a person’s IBD is […]
Butyrate and the Gut Barrier: How It Helps Keep Your Intestinal Lining Sealed
Many people with inflammatory bowel disease (IBD) notice that flare-ups often follow periods of low fibre intake, illness, or disrupted eating patterns, even when nothing obvious has changed in their medication. Part of the explanation may lie in a molecule most patients have never heard of: butyrate. This small but influential compound plays a central […]
Medical Student’s New Zealand Scooter Trip Highlights Toilet Access For IBD
A final-year medical student is scootering the length of New Zealand to raise funds for Crohn’s & Colitis New Zealand (CCNZ) and to draw attention to an everyday concern for people with inflammatory bowel disease (IBD): finding a clean, accessible toilet. His journey highlights a practical issue that affects thousands of people living with Crohn’s […]
Gut Microbiome Patterns May Split IBD Into Two Types
A new multi-omics analysis of 178 people with inflammatory bowel disease (IBD) has identified two distinct gut microbiome enterotypes, patient groupings defined by characteristic combinations of gut bacteria, with markedly different metabolic signatures. The findings suggest that IBD, which includes Crohn’s disease and ulcerative colitis, may encompass biologically distinct subtypes rather than a single uniform […]
Meet Your Butyrate-Making Microbes: The Gut Bacteria That Keep Your Colon Healthy
If you have inflammatory bowel disease (IBD), you have probably heard your gastroenterologist or dietitian mention “the microbiome” as though it were one simple thing. It is not. Your large intestine hosts a vast community of bacteria, and one group within it spends its time producing butyrate, a compound that appears to play a meaningful […]
US Researchers Receive Funding to Study Lingering Colitis Symptoms
Researchers at the University of California, Los Angeles (UCLA) Health and Mount Sinai have received four million US dollars in federal funding to examine why some people with ulcerative colitis continue to experience bowel symptoms even after inflammation has eased. The five-year study could help explain a pattern that affects a significant number of people […]
The Anti-Inflammatory Duo: How EPA and Butyrate May Work Better Together Than Apart
Many people living with Crohn’s disease or ulcerative colitis spend a lot of time thinking about what to eat, hoping certain foods might calm inflammation rather than stir it up. Two substances often mentioned in this context, eicosapentaenoic acid (EPA, a type of omega-3 fat) and butyrate (a short-chain fatty acid made by gut bacteria), […]