Health News

Lead Paragraph Researchers at Monash University have developed miniature, lab-grown intestinal models, known as organoids, using live tissue and bacteria taken from the gut. The models aim to improve understanding of paediatric inflammatory bowel disease (IBD) and could help scientists study how the condition develops in children, a group in which research options have historically […]

A new research review has identified adipose tissue and skeletal muscle composition as potential predictors of biologic treatment response in patients with Crohn’s disease. The findings suggest body composition analysis could help clinicians anticipate which patients may experience treatment failure on biologic therapy. Background Context Biologic therapies have transformed management of moderate to severe Crohn’s […]

Researchers have identified distinct metabolic signatures in stool samples that may help predict which patients with Crohn’s disease are at higher risk of developing complications. The findings, published in a recent metabolomic profiling study, suggest that non-invasive faecal testing could one day support earlier clinical decision making in inflammatory bowel disease (IBD) management. Background Context […]

Two recent studies have identified genetic and cellular markers that may allow clinicians to predict severe inflammatory bowel disease (IBD) earlier and understand why inflammation persists even after visible healing. The findings, drawn from data covering more than 43,000 patients and detailed cellular mapping of gut tissue, suggest that personalised treatment strategies could soon move […]

A new Swedish population study has found that people with inflammatory bowel disease (IBD) face a significantly elevated risk of depression, anxiety, and substance misuse in the years preceding their diagnosis. The findings, reported by CTV News, reinforce observations made by Canadian and international IBD specialists and highlight the importance of recognising psychiatric comorbidity in […]

The University of Miami Miller School of Medicine has announced a new research initiative investigating whether personalised anti-inflammatory dietary interventions can reduce inflammation in people living with Crohn’s disease. The study forms part of the institution’s broader precision medicine approach to inflammatory bowel disease (IBD), which includes identifying genetic variants associated with medication-related adverse effects. […]

Researchers have discovered that approximately 3.5% of people with inflammatory bowel disease (IBD) produce autoantibodies that block interleukin-10, a protein that normally dampens inflammation. The finding, drawn from data involving more than 4,900 patients, links a known genetic risk factor to severe, uncontrolled bowel inflammation and supports the view that IBD encompasses multiple biologically distinct […]

Patients with inflammatory bowel disease face a substantially elevated risk of developing psychiatric disorders, beginning two to three years before IBD diagnosis and persisting for up to a decade afterwards, according to new research reported by News-Medical.Net and Neuroscience News. The findings highlight a significant bidirectional relationship between gastrointestinal and mental health in this patient […]

Guts UK has published advice to help people with digestive conditions make the most of summer without overexerting themselves. The charity suggests a range of activities that can be adapted to individual energy levels and symptom management needs, recognising that warmer weather and changes in routine can affect how the gut behaves. Managing summer with […]

New research has identified a connection between inflammatory bowel disease and reduced activation of TGR5, a bile acid receptor that plays a key role in metabolic and immune regulation. The findings, published in EMJ, suggest that altered bile acid profiles in IBD patients may contribute to ongoing inflammatory activity in the gut. Background Context TGR5, […]