Authors: Wang XJ, Thakur E, Shapiro J Journal: BMJ Year: 2024 Volume: 387 Article number: e075777 DOI: 10.1136/bmj-2023-075777 Study at a glance Study type: State of the art review Studies included: Multiple randomised controlled trials, systematic reviews, and meta-analyses Participants: Adults with irritable bowel syndrome Intervention: Non-pharmaceutical treatments including dietary interventions, brain-gut behaviour therapies, complementary […]
Lifestyle, behaviour, and environmental modification for the management of patients with IBD
Authors: Ashwin N Ananthakrishnan, Gilaad G Kaplan, Charles N Bernstein, Kristin E Burke, Paul J Lochhead, Alexa N Sasson, Manasi Agrawal, Jimmy Ho Tuan Tiong, Joshua Steinberg, Wolfgang Kruis, Flavio Steinwurz, Vineet Ahuja, Siew C Ng, David T Rubin, Jean-Frederic Colombel, Richard Gearry, on behalf of the International Organization for Study of Inflammatory Bowel Diseases […]
AGA Clinical Practice Update on Diet and Nutritional Therapies in Patients With Inflammatory Bowel Disease: Expert Review
Authors: Jana G. Hashash, Jaclyn Elkins, James D. Lewis, and David G. Binion Journal: Gastroenterology Year: 2024 Volume: 166 Pages: 521–532 DOI: 10.1053/j.gastro.2023.11.303 Study at a Glance Study type: Expert review Participants: Not applicable (expert guidance document) Population studied: Patients with inflammatory bowel disease (IBD) Intervention or approach studied: Diet and nutritional therapies, including Mediterranean […]
Three Studies Highlight Shift Towards Precision Medicine in IBD
Three recently reported developments in inflammatory bowel disease (IBD) research underscore a growing shift towards mechanism-based, personalised treatment. The findings address long-standing questions about why Crohn’s disease and ulcerative colitis affect individuals differently and why many patients continue to experience disease instability despite advanced therapies. Background Context IBD encompasses a spectrum of chronic inflammatory conditions […]
Hidden Cell Network May Hold Key to Intestinal Repair in IBD
Researchers have identified a previously unrecognised network of cells in the intestine that could offer new insights into tissue healing and inflammatory bowel disease. The discovery, announced by EurekAlert!, may help explain why some patients experience impaired gut repair and could inform future therapeutic strategies for Crohn’s disease and ulcerative colitis. Background Context The intestinal […]
Modern Advanced Therapies for Inflammatory Bowel Diseases: Practical Considerations and Positioning
Authors: David I. Fudman, Ryan A. McConnell, Christina Ha, and Siddharth Singh Journal: Clinical Gastroenterology and Hepatology Year: 2025 Volume: 23 Pages: 454–468 DOI: https://doi.org/10.1016/j.cgh.2024.06.050 Study at a Glance Study type: Narrative review Participants: Not applicable Population studied: Patients with inflammatory bowel disease Intervention or approach studied: Janus kinase inhibitors, interleukin-23 antagonists, and sphingosine 1-phosphate […]
Diet in Inflammatory Bowel Diseases: Efficacy, Tolerability, and Microbiome Effects Toward Personalized Management
Francesco Calabrese and colleagues from the University of Genoa have published a comprehensive review examining the role of diet as a potential therapeutic tool in inflammatory bowel disease. Their work, published in Digestive Diseases and Sciences in 2025, explores how various dietary approaches may influence symptoms, intestinal inflammation, the gut microbiome, and mucosal repair in […]
Irritable Bowel Syndrome in Inflammatory Bowel Disease: An Evidence-Based Practical Review
Authors: Mohsin F. Butt, Mustafa H. Reghefaoui, Aaron Shailesh Benedict, Maiss Reghefaoui, Hussain Al-Jabir, Aneeqa Shaikh, Katarina Vojtekova, Gordon W. Moran, Maura Corsetti and Qasim Aziz Journal: Journal of Clinical Medicine Year: 2025 Volume: 15 Page number: 116 DOI: 10.3390/jcm15010116 Study at a Glance Study type: Narrative review Participants: Patients with quiescent inflammatory bowel disease […]
New UK campaign launches to break the silence around digestive symptoms
Guts UK, the national charity for the digestive system, has launched a week-long campaign encouraging people to talk more openly about their gut health. The Let’s Talk Guts campaign, running from 13 to 19 July, aims to reduce embarrassment and help people feel more confident discussing digestive symptoms with family, friends, employers, and healthcare professionals. […]
Stress and the Gut-Brain Axis: Why Your Mind Affects Your Gut More Than You Think
Understanding the gut-brain connection If you’ve ever noticed that stress makes your gut symptoms worse, you’re not imagining it. The gut and brain are in constant communication, and when you feel stressed, anxious or overwhelmed, your digestive system often reacts. For people living with Crohn’s disease or ulcerative colitis, this connection can feel especially strong. […]