A new study has found that people living with inflammatory bowel disease (IBD) are not at increased risk of high blood pressure problems during pregnancy overall, although certain specific risks, including preeclampsia, were higher. The findings may reassure many people with IBD who are pregnant or planning a pregnancy, while highlighting the value of closer […]
Coping With Uncertainty: Managing the Anxiety of Never Knowing When a Flare Will Strike
Living with Crohn’s disease or ulcerative colitis often means living with a question mark. Even when bloodwork looks stable and symptoms are quiet, many people find themselves scanning their body for early warning signs, wondering if today is the day things turn. This constant watchfulness, and the anxiety it brings, is one of the least […]
Health Anxiety and Your Gut: When Worrying About Symptoms Becomes Its Own Problem
Many people with inflammatory bowel disease (IBD), a group of conditions including Crohn’s disease and ulcerative colitis that cause chronic inflammation of the digestive tract, know the unease of noticing a new twinge or change in bowel habit. A cramp after lunch can trigger a spiral of questions: is this a flare starting, or something […]
Body Image, Scars and Self-Esteem: The Emotional Side of Living With IBD
Getting dressed, going swimming, or being intimate with a partner can feel complicated when your body carries the visible or hidden marks of inflammatory bowel disease (IBD). Surgical scars, a stoma bag, sudden weight changes from medication, or the simple unpredictability of needing a toilet urgently can quietly reshape how someone sees themselves. These experiences […]
Early Top-Down Therapy Shows Lasting Crohn’s Benefit
Lead Paragraph New follow-up data reported by DocWire News indicate that clinical benefits associated with early “top-down” treatment for moderate to severe Crohn’s disease persisted over five years. The findings add to the evidence base supporting earlier use of advanced therapies rather than waiting for conventional treatments to fail, a distinction relevant to gastroenterologists managing […]
CBT for IBS and IBD: How Talking Therapy Can Ease Gut Symptoms
For many people living with inflammatory bowel disease (IBD), a stressful week at work or a poor night’s sleep seems to translate directly into a bad gut day, more urgency, more discomfort, more time spent thinking about symptoms. This link between mind and gut is not imagined. It reflects a genuine, measurable communication system between […]
FDA Clears IND Application for Crohn’s Therapy
Palisade Bio has announced that the US Food and Drug Administration (FDA) has cleared its Investigational New Drug (IND) application for PALI-2108 in Crohn’s disease. The clearance allows the compound to progress into clinical testing for this indication, building on the company’s existing development programme in ulcerative colitis (UC) and marking an expansion of its […]
Gut Microbiota in Mucosa and Feces of Newly Diagnosed, Treatment-Naïve Adult Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients
Authors: Čipčić Paljetak H, Barešić A, Panek M, Perić M, Matijašić M, Lojkić I, Barišić A, Vranešić Bender D, Ljubas Kelečić D, Brinar M, Kalauz M, Miličević M, Grgić D, Turk N, Karas I, Čuković-Čavka S, Krznarić Ž, Verbanac D. Published in Gut Microbes, 2022. DOI: 10.1080/19490976.2022.2083419 Background & Rationale Crohn’s disease (CD) and ulcerative […]
IBD Diagnoses in Brazil Climb Fivefold Over 13 Years
New research presented at a Brazilian medical conference suggests that inflammatory bowel disease (IBD), which includes Crohn’s disease and ulcerative colitis, has become far more common in Brazil over the past decade. The findings matter because they point to a wider global pattern, with more people, including younger adults, potentially living with these lifelong digestive […]
Oral Candida Strains Found Migrating Into the Gut in IBD
A new study reported in Nature Medicine has identified strains of the fungus Candida moving from the mouth into the gut in people with inflammatory bowel disease (IBD), according to research discussed by Iliyan D. Iliev, PhD, of Weill Cornell Medicine. The findings add to growing evidence that the oral and intestinal microbiomes are more […]